365 citations · 2k across the 65 of their papers we have counts for
13 papers · 1 filter
Optimal Control in Stochastic Thermodynamics
Steven Blaber, David A. Sivak
We review recent progress in optimal control in stochastic thermodynamics. Theoretical advances provide in-depth insight into minimum-dissipation control with either full or limite…
Optimal Control of the F-ATPase Molecular Motor
Deepak Gupta, Steven J. Large, Shoichi Toyabe +1
F-ATPase is a rotary molecular motor that \emph{in vivo} is subject to strong nonequilibrium driving forces. There is great interest in understanding the operational principl…
Inferring Subsystem Efficiencies in Bipartite Molecular Machines
Matthew P. Leighton, David A. Sivak
Molecular machines composed of coupled subsystems transduce free energy between different external reservoirs, in the process internally transducing energy and information. While s…
Energy and information flows in autonomous systems
Jannik Ehrich, David A. Sivak
Multi-component molecular machines are ubiquitous in biology. We review recent progress on describing their thermodynamic properties using autonomous bipartite Markovian dynamics.…
Connections between efficient control and spontaneous transitions in an Ising model
Miranda D. Louwerse, David A. Sivak
A system can be driven between metastable configurations by a time-dependent driving protocol, which uses external control parameters to change the potential energy of the system.…
Therapeutic algebra of immunomodulatory drug responses at single-cell resolution
Jialong Jiang, Sisi Chen, Tiffany Tsou +10
Therapeutic modulation of immune states is central to the treatment of human disease. However, how drugs and drug combinations impact the diverse cell types in the human immune sys…