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physics.bio-ph2026
Co-condensation and multivalency enable acetylation-sensitive, concentration-robust assembly of BRD4 condensates
Yury Polyachenko, Hans-Frederick Watanabe, Alexei Korolev +1
Biomolecular condensates must assemble at specific locations and times inside living cells to perform their biological functions. However, it remains unclear whether condensate for…
cond-mat.soft2026
A thermodynamic metric quantitatively predicts disordered protein partitioning and multicomponent phase behavior
Zhuang Liu, Beijia Yuan, Mihir Rao +2
Intrinsically disordered regions (IDRs) of proteins mediate sequence-specific interactions underlying diverse cellular processes, including the formation of biomolecular condensate…