404 citations · 4.7k across the 72 of their papers we have counts for
3 papers · 1 filter
Allosteric control in icosahedral capsid assembly
Guillermo R. Lazaro, Michael F. Hagan
During the lifecycle of a virus, viral proteins and other components self-assemble to form a symmetric protein shell called a capsid. This assembly process is subject to multiple c…
Virus Assembly on a Membrane is Facilitated by Membrane Microdomains
Teresa Ruiz-Herrero, Michael F. Hagan
For many viruses assembly and budding occur simultaneously during virion formation. Understanding the mechanisms underlying this process could promote biomedical efforts to block v…
Mechanisms of budding of nanoscale particles through lipid bilayers
Teresa Ruiz-Herrero, Enrique Velasco, Michael F. Hagan
We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determ…