75 citations · 75 across the 3 of their papers we have counts for
3 papers
q-bio.QM2007
Cross-Scale Sensitivity Analysis of a Non-Small Cell Lung Cancer Model: Linking Molecular Signaling Properties to Cellular Behavior
Zhihui Wang, Christina M. Birch, Thomas S. Deisboeck
Sensitivity analysis is an effective tool for systematically identifying specific perturbations in parameters that have significant effects on the behavior of a given biosystem, at…
q-bio.TO2006★ 75 cited
Simulating Brain Tumor Heterogeneity with a Multiscale Agent-Based Model: Linking Molecular Signatures, Phenotypes and Expansion Rate
Le Zhang, Costas G. Strouthos, Zhihui Wang +1
We have extended our previously developed 3D multi-scale agent-based brain tumor model to simulate cancer heterogeneity and to analyze its impact across the scales of interest. Whi…
q-bio.TO2006
Cancer Dissemination: A Consequence of limited Carrying Capacity?
Thomas S. Deisboeck, Zhihui Wang
Assuming that there is feedback between an expanding cancer system and its organ-typical microenvironment, we argue here that such local tumor growth is guided by co-existence rath…