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q-bio.OT2023
Sequence Evolution, Structure and Dynamics of Transmembrane Proteins: Rhodopsin
J. C. Phillips
Rhodopsin is a G-protein coupled receptor found in retinal rod cells, where it mediates monocrhromatic vision in dim light. It is one of the most studied proteins with thousands of…
q-bio.OT2023
Evolution of Two Membrane Protein Sequences and Functions
J. C. Phillips
TRPC(3,6) are two ~ 930 amino acid membrane proteins that form calcium permeant cation channels. Here we examine the differences between mammals and oviparous species. Our method i…
q-bio.OT2023
Functional Differences of MIP (Lens Fiber Major Intrinsic Protein) Between Animals and Birds
J. C. Phillips
The major intrinsic protein (MIP) of the lens fiber cell membrane plays a role in lens biogenesis and maintenance. Its polypeptide chains span the membrane six times, and the prote…