175 citations · 642 across the 73 of their papers we have counts for
73 papers
How Life Works: Darwinian Evolution of Proteins
J. C. Phillips
We review the development of thermodynamic protein hydropathic scaling theory, starting from backgrounds in mathematics and statistical mechanics, and leading to biomedical applica…
Asymptomatic Phase and Convergent Evolution of Coronavirus
J. C. Phillips
CoV2019 has evolved to be much more dangerous than CoV2003. Experiments suggest that structural rearrangements dramatically enhance CoV2019 activity. We identify a new first stage…
Kinesin Motors and the Evolution of Intelligence
J. C. Phillips
Intelligence is often discussed in terms of neural networks in the cerebral cortex, whose evolution has presumably been influenced by Darwinian selection. Here we present molecular…
Self-Organized Networks: Darwinian Evolution of Myosin-1
J. C. Phillips
Cytoskeletons are self-organized networks based on polymerized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin and dynein. Their positive Darwinian…
Darwinian Evolution of Taste
J. C. Phillips
What is life. Schrodingers question is discussed here for a specific protein, villin, which builds cells in tissues that detect taste and sound. Villin is represented by a sequence…
Synchronized Attachment and the Darwinian Evolution of Coronaviruses CoV-1 and CoV-2
J. C. Phillips
CoV2019 has evolved to be much more dangerous than CoV2003. Experiments suggest that structural rearrangements dramatically enhance CoV2019 activity. We identify a new first stage…