3 papers
q-bio.BM2022
TIDAL: Topology-Inferred Drug Addiction Learning
Zhu Zailiang, Dou Bozheng, Cao Yukang +8
Drug addiction or drug overdose is a global public health crisis, and the design of anti-addiction drugs remains a major challenge due to intricate mechanisms. Since experimental d…
q-bio.MN2022
Machine learning analysis of cocaine addiction informed by DAT, SERT, and NET-based interactome networks
Hongsong Feng, Kaifu Gao, Dong Chen +3
Cocaine addiction is a psychosocial disorder induced by the chronic use of cocaine and causes a large of number deaths around the world. Despite many decades' effort, no drugs have…
q-bio.MN2021
Proteome-informed machine learning studies of cocaine addiction
Kaifu Gao, Dong Chen, Alfred J Robison +1
Cocaine addiction accounts for a large portion of substance use disorders and threatens millions of lives worldwide. There is an urgent need to come up with efficient anti-cocaine…