most citedEarly completion based on multiple dosages to accelerate maximum tolerated dose-finding

2 citations · 2 across the 6 of their papers we have counts for

collaborators

6 papers

stat.ME2022

Variable Selection using Inverse Survival Probability Weighting

Masahiro Kojima

In this paper, we propose two variable selection methods for adjusting the censoring information for survival times, such as the restricted mean survival time. To adjust for the in…

stat.ME2022

Comparison of Baseline Covariate Adjustment Methods for Restricted Mean Survival Time

Keisuke Hanada, Junji Moriya, Masahiro Kojima

The restricted mean survival time is a clinically easy-to-interpret measure that does not require any assumption of proportional hazards. We focus on two ways to directly model the…

stat.ME2022

Data-Dependent Early Completion of Dose Finding Trials for Drug-Combination

Masahiro Kojima

We propose a data-dependent early completion of dose finding trials for drug-combination. The early completion is determined when a beta-binomial probability for dose retainment wi…

stat.ME2021

Adaptive design for identifying maximum tolerated dose early to accelerate dose-finding trial

Masahiro Kojima

Purpose: The early identification of maximum tolerated dose (MTD) in phase I trial leads to faster progression to a phase II trial or an expansion cohort to confirm efficacy. Metho…

q-bio.QM20212 cited

Early completion based on multiple dosages to accelerate maximum tolerated dose-finding

Masahiro Kojima

Background: Phase I trials desire to identify the maximum tolerated dose (MTD) early and proceed quickly to an expansion cohort or phase II trial for efficacy. We propose an early…

stat.ME2021

Adaptive Contrast Test for Dose-Response Studies and Modeling

Masahiro Kojima

We propose a powerful adaptive contrast test with ordinal constraint contrast coefficients determined by observed responses. The adaptive contrast test can perform using easily cal…