36 citations · 38 across the 11 of their papers we have counts for
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stat.ME2021
Adaptive design for identifying maximum tolerated dose early to accelerate dose-finding trial
Masahiro Kojima
Purpose: The early identification of maximum tolerated dose (MTD) in phase I trial leads to faster progression to a phase II trial or an expansion cohort to confirm efficacy. Metho…
q-bio.QM2021★ 2 cited
Early completion based on multiple dosages to accelerate maximum tolerated dose-finding
Masahiro Kojima
Background: Phase I trials desire to identify the maximum tolerated dose (MTD) early and proceed quickly to an expansion cohort or phase II trial for efficacy. We propose an early…
stat.ME2021
Adaptive Contrast Test for Dose-Response Studies and Modeling
Masahiro Kojima
We propose a powerful adaptive contrast test with ordinal constraint contrast coefficients determined by observed responses. The adaptive contrast test can perform using easily cal…