activity
20212026
most citedSpatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment

30 citations · 67 across the 12 of their papers we have counts for

collaborators

12 papers

q-bio.CB2026

Hydrodynamic theories of chemotaxis-driven invasion in proliferating cell populations

Giulia L. Celora, Martina Conte

Biased migration up chemical gradients and proliferation are fundamental drivers of collective invasion in several biological processes ranging from embryonic morphogenesis to canc…

q-bio.CB2026

Coupled chemotactic fronts in heterogeneous sensor-consumer cell mixtures

Marjorie Watts, Carles Falcó, Giulia L. Celora

Chemotaxis underlies the collective migration of cell populations in developmental processes and immune responses. While the theoretical investigation of single-cell-type collectiv…

q-bio.CB2026

A nonlinear theory for chemotactic fronts of mixed populations

Giulia L. Celora, Marjorie Watts, Carles Falcó +1

Collective migration of heterogeneous cell populations is central to many biological and physiological processes, including development and immune response. Recent experimental and…

cond-mat.soft2026

Chemotaxis of cell aggregates: morphology and dynamics of migrating active droplets

Giulia L. Celora, Benjamin J. Walker, Mohit P. Dalwadi +1

Biological tissues have been observed to display emergent fluid-like properties, owing to physical interactions between cells. However, it remains unclear in general how these flui…

cond-mat.soft2025

The diffusive dynamics and electrochemical regulation of weak polyelectrolytes across liquid interfaces

Giulia Laura Celora, Ralf Blossey, Andreas Munch +1

We propose a framework to study the spatio-temporal evolution of liquid-liquid phase separation of weak polyelectrolytes in ionic solutions. Unlike strong polyelectrolytes, which c…

cond-mat.soft2023★ 6 cited

Counterion-controlled phase equilibria in a charge-regulated polymer solution

Giulia L. Celora, Ralf Blossey, Andreas Münch +1

We study phase equilibria in a minimal model of charge-regulated polymer solutions. Our model consists of a single polymer species whose charge state arises from protonation-deprot…

q-bio.TO2022

Minimal Morphoelastic Models of Solid Tumour Spheroids: A Tutorial

Benjamin J. Walker, Giulia L. Celora, Alain Goriely +2

Tumour spheroids have been the focus of a variety of mathematical models, ranging from Greenspan's classical study of the 1970s through to contemporary agent-based models. Of the m…

cond-mat.soft2022★ 1 cited

The electric double layer at the interface between a polyelectrolyte gel and salt bath

Matthew G. Hennessy, Giulia L. Celora, Andreas Münch +2

The electric double layer (EDL) that forms at the interface between a polyelectrolyte gel and a salt bath is studied using asymptotic and numerical methods. Specifically, matched a…

q-bio.CB2021★ 30 cited

Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment

Giulia L. Celora, Helen M. Byrne, P. G. Kevrekidis

We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stem…

cond-mat.soft2021★ 23 cited

A kinetic model of a polyelectrolyte gel undergoing phase separation

Giulia L. Celora, Matthew G. Hennessy, Andreas Münch +2

In this study we use non-equilibrium thermodynamics to systematically derive a phase-field model of a polyelectrolyte gel coupled to a hydrodynamic model for a salt solution surrou…

cond-mat.soft2021★ 7 cited

The dynamics of a collapsing polyelectrolyte gel

Giulia L. Celora, Matthew G. Hennessy, Andreas Münch +2

We analyse the dynamics of different routes to collapse of a constrained polyelectrolyte gel in contact with an ionic bath. The evolution of the gel is described by a model that in…

q-bio.CB2021

Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia

Giulia L. Celora, Helen M. Byrne, Christos Zois +1

In cancer, treatment failure and disease recurrence have been associated with small subpopulations of cancer cells with a stem-like phenotype. In this paper, we develop and investi…