30 citations · 67 across the 12 of their papers we have counts for
4 papers · 1 filter
Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
Giulia L. Celora, Helen M. Byrne, P. G. Kevrekidis
We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stem…
A kinetic model of a polyelectrolyte gel undergoing phase separation
Giulia L. Celora, Matthew G. Hennessy, Andreas Münch +2
In this study we use non-equilibrium thermodynamics to systematically derive a phase-field model of a polyelectrolyte gel coupled to a hydrodynamic model for a salt solution surrou…
The dynamics of a collapsing polyelectrolyte gel
Giulia L. Celora, Matthew G. Hennessy, Andreas Münch +2
We analyse the dynamics of different routes to collapse of a constrained polyelectrolyte gel in contact with an ionic bath. The evolution of the gel is described by a model that in…
Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia
Giulia L. Celora, Helen M. Byrne, Christos Zois +1
In cancer, treatment failure and disease recurrence have been associated with small subpopulations of cancer cells with a stem-like phenotype. In this paper, we develop and investi…