30 citations · 67 across the 12 of their papers we have counts for
5 papers · 1 filter
Hydrodynamic theories of chemotaxis-driven invasion in proliferating cell populations
Giulia L. Celora, Martina Conte
Biased migration up chemical gradients and proliferation are fundamental drivers of collective invasion in several biological processes ranging from embryonic morphogenesis to canc…
Coupled chemotactic fronts in heterogeneous sensor-consumer cell mixtures
Marjorie Watts, Carles Falcó, Giulia L. Celora
Chemotaxis underlies the collective migration of cell populations in developmental processes and immune responses. While the theoretical investigation of single-cell-type collectiv…
A nonlinear theory for chemotactic fronts of mixed populations
Giulia L. Celora, Marjorie Watts, Carles Falcó +1
Collective migration of heterogeneous cell populations is central to many biological and physiological processes, including development and immune response. Recent experimental and…
Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
Giulia L. Celora, Helen M. Byrne, P. G. Kevrekidis
We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stem…
Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia
Giulia L. Celora, Helen M. Byrne, Christos Zois +1
In cancer, treatment failure and disease recurrence have been associated with small subpopulations of cancer cells with a stem-like phenotype. In this paper, we develop and investi…