77 citations · 219 across the 23 of their papers we have counts for
23 papers
Evaluation of the uncertainty in calculating nanodosimetric quantities due to the use of different interaction cross sections in Monte Carlo track structure codes
Carmen Villagrasa, Giorgio Baiocco, Zine-El-Abidine Chaoui +11
This study evaluates the uncertainty in nanodosimetric calculations caused by variations in interaction cross sections within Monte Carlo Track Structure (MCTS) simulation codes. N…
Radial dependence of ionization clustering around a gold nanoparticle
Leo Thomas, Miriam Schwarze, Hans Rabus
This work explores the enhancement of ionization clusters around a gold nanoparticle (NP), indicative of the induction of DNA lesions, a potential trigger for cell-death. Monte Car…
Intercomparison exercise on Monte Carlo simulations of electron spectra and energy depositions by a single gold nanoparticle under X-ray irradiation
Wei Bo Li, Hans Rabus, Carmen Villagrasa +1
Computational approaches, such as Monte Carlo (MC) radiation transport simulations, are used to estimate the dosimetric effects of GNPs, where results differing by orders of magnit…
Nanodosimetric investigation of the track structure of therapeutic carbon ion radiation. Part 1: Measurement of ionization cluster size distributions
Gerhard Hilgers, Miriam Schwarze, Hans Rabus
At the Heidelberg Ion-Beam Therapy Center, the track structure of carbon ions of therapeutic energy after penetrating layers of simulated tissue was investigated for the first time…
Comment on "Reproducibility study of Monte Carlo simulations for nanoparticle dose enhancement and biological modeling of cell survival curves" by Velten et al. [Biomed Phys Eng Express 2023;9:045004]
Hans Rabus
This comment highlights two methodological issues with the recent article by Velten et al. [Biomed Phys Eng Express 2023;9:045004]
Article Commentary on "Microdosimetric and radiobiological effects of gold nanoparticles at therapeutic radiation energies" [T.M. Gray et al., IJRB 2023, 99(2), 308-317]
Hans Rabus, Miriam Schwarze, Leo Thomas
In the recently published article by T.M. Gray et al. "Microdosimetric and radiobiological effects of gold nanoparticles at therapeutic radiation energies" (IJRB 2023, 99(2), 308-3…
Comment on "Biological modeling of gold nanoparticle enhanced radiotherapy for proton therapy" by Lin et al. [Phys. Med. Biol. 60 (2015) 4149-4168]
Hans Rabus
In their article published in Phys. Med. Biol. 60 (2015) 4149-4168, Lin et al studied the radiosensitizing effect of gold nanoparticles (GNPs) using radiation transport simulations…
Comment on "Comparing gold nano-particle enhanced radiotherapy with protons, megavoltage photons and kilovoltage photons: A Monte Carlo simulation" by Lin et al [Phys. Med. Biol. 59 (2014) 7675-7689]
Hans Rabus
In their article published in Phys. Med. Biol. 59 (2014) 7675-7689, Lin et al studied the dose enhancement of of gold nanoparticles (GNPs) for proton therapy, which they compared w…
Experimental benchmark data for Monte Carlo simulated radiation effects of gold nanoparticles. Part II: Comparison of measured and simulated electron spectra from gold nanofoils
Jorge Borbinha, Liset de la Fuente Rosales, Philine Hepperle +4
Electron emission spectra of a thin gold foil after photon interaction were measured over the energy range between 50 eV and 9500 eV to provide reference data for Monte Carlo radia…
Experimental benchmark data for Monte Carlo simulated radiation effects of gold nanoparticles. Part I: Experiment and raw data analysis
Hans Rabus, Philine Hepperle, Christoph Schlueter +2
Electron emission spectra of gold nanoparticles (AuNPs) after photon interaction were measured over the energy range between 50 eV and 9500 eV to provide reference data for Monte C…
Repair kinetics of DSB-foci induced by proton and helium ion microbeams of different energies
Ana Belchior, João F. Canhoto, Ulrich Giesen +3
In this work, the induction and repair of radiation-induced 53BP1 foci were studied in human umbilical vein endothelial cells irradiated at the PTB microbeam with protons and α-par…
Correlated ionisations in two spatially separated nanometric volumes in the track structure of 241Am alpha particles: comparison with Monte Carlo simulations
Gerhard Hilgers, Thomas Braunroth, Hans Rabus
The production of two double strand breaks in spatially separated locations on the DNA molecule can cause the loss of a whole DNA loop, which can be of substantial length depending…
Lessons learnt from the recent EURADOS intercomparisons in computational dosimetry
Hans Rabus, Maria Zankl, Jose Maria Gomez-Ros +5
Organized by Working Group 6 "Computational Dosimetry" of the European Radiation Dosimetry Group (EURADOS), a group of intercomparison exercises was conducted in which participants…
A new Standard DNA damage (SDD) data format
J. Schuemann, A. McNamara, J. W. Warmenhoven +48
Our understanding of radiation induced cellular damage has greatly improved over the past decades. Despite this progress, there are still many obstacles to fully understanding how…
Electrical Characterization of DNA Origami Structures with PEG-PLL coating for improved robustness
Florian Heimbach, Johann Bohlen, Hans Rabus +2
Electrical conductivity of DNA has been a controversial topic since it was first proposed in 1962. Disparities in the experimental results can often be explained by differences of…
Intercomparison of micro- and nanodosimetry Monte Carlo simulations: an approach to assess the influence of different cross-sections for low-energy electrons on the dispersion of results
Carmen Villagrasa, Hans Rabus, Giorgio Baiocco +8
An intercomparison of microdosimetric and nanodosimetric quantities simulated Monte Carlo codes is in progress with the goal of assessing the uncertainty contribution to simulated…
Characterisation of the PTB ion counter nanodosimeter's target volume and its equivalent size in terms of liquid H2O
Gerhard Hilgers, Thomas Braunroth, Hans Rabus
For the first time a dedicated investigation of the target size of a nanodosimeter device has been carried out in order to investigate to what extent measured ionisation cluster si…
Consistency checks of results from a Monte Carlo code intercomparison for emitted electron spectra and energy deposition around a single gold nanoparticle irradiated by X-rays
H. Rabus, W. B. Li, H. Nettelbeck +9
Organized by the European Radiation Dosimetry Group (EURADOS), a Monte Carlo code intercomparison exercise was conducted where participants simulated the emitted electron spectra a…
Investigation into the foundations of the track-event theory of cell survival and the radiation action model based on nanodosimetry
Sonwabile Arthur Ngcezu, Hans Rabus
This work aims at carving out more clearly the basic assumptions behind the "track-event theory" (TET) and its derivate radiation action model based on nanodosimetry (RAMN) by clea…
Is the track-event theory of cell survival internally consistent?
Sonwabile Arthur Ngcezu, Hans Rabus
The "track event theory" (TET) has been developed in recent years as an alternative to the phenomenological linear-quadratic model for cell survival under exposure to ionizing radi…
Intercomparison of Monte Carlo calculated dose enhancement ratios for gold nanoparticles irradiated by X-rays: assessing the uncertainty and correct methodology for extended beams
H. Rabus, W. B. Li, C. Villagrasa +10
Results of a Monte Carlo code intercomparison exercise for simulations of the dose enhancement from a gold nanoparticle (GNP) irradiated by X-rays have been recently reported. To h…
Nanodosimetry - on the tracks of biological radiation effectiveness
Hans Rabus
Biological effectiveness of a certain absorbed dose of ionizing radiation depends on the radiation quality, i. e. the spectrum of ionizing particles and their energy distribution.…
Measurement of track structure parameters of low and medium energy helium and carbon ions in nanometric volumes
G. Hilgers, M. U. Bug, H. Rabus
Ionisation cluster size distributions produced in the sensitive volume of an ion-counting wall-less nanodosimeter by monoenergetic carbon ions with energies between 45 MeV and 150…