Comment on "Reproducibility study of Monte Carlo simulations for nanoparticle dose enhancement and biological modeling of cell survival curves" by Velten et al. [Biomed Phys Eng Express 2023;9:045004]
arXiv:2308.06541 · doi:10.1088/2057-1976/ad1731
Abstract
This comment highlights two methodological issues with the recent article by Velten et al. [Biomed Phys Eng Express 2023;9:045004]
14 pages, 6 figures. Two Figures, an estimate of concrete numerical values and 3 Supplements have been added. Suppl. 1: mathematical derivation of the expression for the background dose, Suppl. 2: modification when the LQL-model is used instead of the LQ-model for cell survival. Suppl. 3: sample comparison of the predicted lesions with the "LEM in 2D" versus the conventional LEM