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q-bio.SC2026
Amplifying gene expression sensitivity by surface condensation on DNA
Tarek Tohme, Henry Alston, Jacqueline Janssen +2
Condensation of proteins on DNA is a central aspect of genome organisation, and has been proposed as a mechanism of gene regulation in eukaryotes, notably by mediating the action o…
q-bio.SC2025
Theoretical limits for sensing through phase separation
Henry Alston, Mason Rouches, Arvind Murugan +2
Biomolecular condensates form on timescales of seconds in cells upon environmental or compositional changes. Condensate formation is thus argued to act as a mechanism for sensing s…