Showing q-bio.BMShow all
2 papers · 1 filter
q-bio.BM2025
Paraplume: A fast and accurate paratope prediction method provides insights into repertoire-scale binding dynamics
Gabriel Athènes, Adam Woolfe, Thierry Mora +1
The specific region of an antibody responsible for binding to an antigen, known as the paratope, is essential for immune recognition. Accurate identification of this small yet crit…
q-bio.BM2024
Energy-based generative models for monoclonal antibodies
Paul Pereira, Hervé Minoux, Aleksandra M. Walczak +1
Since the approval of the first antibody drug in 1986, a total of 162 antibodies have been approved for a wide range of therapeutic areas, including cancer, autoimmune, infectious,…