3 papers
physics.optics2020
Localization microscopy: a review of the progress in methods and applications
Jack W Shepherd, Mark C Leake
Here, we report analysis and summary of research in the field of localization microscopy for optical imaging. We introduce the basic elements of super-resolved localization microsc…
q-bio.CB2020
Molecular crowding in single eukaryotic cells: using cell environment biosensing and single-molecule optical microscopy to probe dependence on extracellular ionic strength, local glucose conditions, and sensor copy number
Jack W Shepherd, Sarah Lecinski, Jasmine Wragg +3
The physical and chemical environment inside cells is of fundamental importance to all life but has traditionally been difficult to determine on a subcellular basis. Here we combin…
q-bio.BM2019
The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA
Jack W Shepherd, Robert J Greenall, Matt I J Probert +2
The double-helical structure of DNA results from canonical base pairing and stacking interactions. However, variations from steady-state conformations result from mechanical pertur…