46 citations · 79 across the 7 of their papers we have counts for
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stat.AP2026
A Bayesian Phase I/II basket design with robust information borrowing to identify subtrial-specific optimal biological doses
Zhi Cao, Haiyan Zheng, Pavel Mozgunov
The objective of modern early oncology dose-finding is to identify an optimal biological dose (OBD), rather than simply the maximum tolerated dose. In basket trials, the dose-toxic…
stat.AP2019★ 11 cited
A Bayesian decision-theoretic approach to incorporate preclinical information into phase I oncology trials
Haiyan Zheng, Lisa V. Hampson
Leveraging preclinical animal data for a phase I first-in-man trial is appealing yet challenging. A prior based on animal data may place large probability mass on values of the dos…