51 citations · 211 across the 9 of their papers we have counts for
Showing 2019Show all
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q-bio.CB2019★ 17 cited
When Two are Better than One: Modeling the Mechanisms of Antibody Mixtures
Tal Einav, Jesse D Bloom
It is difficult to predict how antibodies will behave when mixed together, even after each has been independently characterized. Here, we present a statistical mechanical model for…
q-bio.GN2019★ 49 cited
The Energetics of Molecular Adaptation in Transcriptional Regulation
Griffin Chure, Manuel Razo-Mejia, Nathan M. Belliveau +5
Mutation is a critical mechanism by which evolution explores the functional landscape of proteins. Despite our ability to experimentally inflict mutations at will, it remains diffi…
q-bio.SC2019★ 51 cited
How the Avidity of Polymerase Binding to the -35/-10 Promoter Sites Affects Gene Expression
Tal Einav, Rob Phillips
Although the key promoter elements necessary to drive transcription in Escherichia coli have long been understood, we still cannot predict the behavior of arbitrary novel promoters…