51 citations · 211 across the 9 of their papers we have counts for
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q-bio.BM2018
Combinatorial Control through Allostery
Vahe Galstyan, Luke Funk, Tal Einav +1
Many instances of cellular signaling and transcriptional regulation involve switch-like molecular responses to the presence or absence of input ligands. To understand how these res…
q-bio.BM2018★ 40 cited
Harnessing Avidity: Quantifying Entropic and Energetic Effects of Linker Length and Rigidity Required for Multivalent Binding of Antibodies to HIV-1 Spikes
Tal Einav, Shahrzad Yazdi, Aaron Coey +2
Due to the low density of envelope (Env) spikes on the surface of HIV-1, neutralizing IgG antibodies rarely bind bivalently using both antigen-binding arms (Fabs) to crosslink betw…