31 citations · 64 across the 16 of their papers we have counts for
Showing 2019Show all
2 papers · 1 filter
stat.AP2019★ 1 cited
The use of registry data to extrapolate overall survival results from randomised controlled trials
Reynaldo Martina, Keith Abrams, Sylwia Bujkiewicz +5
Background: Pre-marketing authorisation estimates of survival are generally restricted to those observed directly in randomised controlled trials (RCTs). However, for regulatory an…
stat.ME2019
A Bayesian hierarchical meta-analytic method for modelling surrogate relationships that vary across treatment classes using aggregate data
Tasos Papanikos, John Thompson, Keith Abrams +4
Surrogate endpoints play an important role in drug development when they can be used to measure treatment effect early compared to the final clinical outcome and to predict clinica…