1 citations · 1 across the 1 of their papers we have counts for
3 papers
The use of registry data to extrapolate overall survival results from randomised controlled trials
Reynaldo Martina, Keith Abrams, Sylwia Bujkiewicz +5
Background: Pre-marketing authorisation estimates of survival are generally restricted to those observed directly in randomised controlled trials (RCTs). However, for regulatory an…
A Bayesian hierarchical meta-analytic method for modelling surrogate relationships that vary across treatment classes using aggregate data
Tasos Papanikos, John Thompson, Keith Abrams +4
Surrogate endpoints play an important role in drug development when they can be used to measure treatment effect early compared to the final clinical outcome and to predict clinica…
Combining tumour response and progression free survival as surrogate endpoints for overall survival in advanced colorectal cancer
Eleni G. Elia, Nicolas Städler, Oriana Ciani +2
Progression free survival (PFS) and tumour response (TR) have been investigated as surrogate endpoints for overall survival (OS) in advanced colorectal cancer (aCRC), however their…