354 citations · 1.3k across the 21 of their papers we have counts for
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Deep learning-enabled virtual multiplexed immunostaining of label-free tissue for vascular invasion assessment
Yijie Zhang, Cagatay Isil, Xilin Yang +6
Immunohistochemistry (IHC) has transformed clinical pathology by enabling the visualization of specific proteins within tissue sections. However, traditional IHC requires one tissu…
Label-free evaluation of lung and heart transplant biopsies using tissue autofluorescence-based virtual staining
Yuzhu Li, Nir Pillar, Tairan Liu +12
Organ transplantation serves as the primary therapeutic strategy for end-stage organ failures. However, allograft rejection is a common complication of organ transplantation. Histo…
Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning
Xilin Yang, Bijie Bai, Yijie Zhang +8
Systemic amyloidosis is a group of diseases characterized by the deposition of misfolded proteins in various organs and tissues, leading to progressive organ dysfunction and failur…
A paper-based multiplexed serological test to monitor immunity against SARS-CoV-2 using machine learning
Merve Eryilmaz, Artem Goncharov, Gyeo-Re Han +6
The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high…
Virtual histological staining of unlabeled autopsy tissue
Yuzhu Li, Nir Pillar, Jingxi Li +12
Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior s…
Deep Learning-enabled Virtual Histological Staining of Biological Samples
Bijie Bai, Xilin Yang, Yuzhu Li +3
Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromat…
Virtual stain transfer in histology via cascaded deep neural networks
Xilin Yang, Bijie Bai, Yijie Zhang +4
Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types of stains are applied to bring contrast to and highlig…