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20202025
most citedDeep Learning-enabled Virtual Histological Staining of Biological Samples

354 citations · 1.3k across the 21 of their papers we have counts for

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6 papers · 1 filter

eess.IV2024★ 27 cited

Pixel super-resolved virtual staining of label-free tissue using diffusion models

Yijie Zhang, Luzhe Huang, Nir Pillar +3

Virtual staining of tissue offers a powerful tool for transforming label-free microscopy images of unstained tissue into equivalents of histochemically stained samples. This study…

eess.IV2024★ 35 cited

Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling

Sahan Yoruc Selcuk, Xilin Yang, Bijie Bai +12

Human epidermal growth factor receptor 2 (HER2) is a critical protein in cancer cell growth that signifies the aggressiveness of breast cancer (BC) and helps predict its prognosis.…

eess.IV2022★ 28 cited

Virtual staining of defocused autofluorescence images of unlabeled tissue using deep neural networks

Yijie Zhang, Luzhe Huang, Tairan Liu +5

Deep learning-based virtual staining was developed to introduce image contrast to label-free tissue sections, digitally matching the histological staining, which is time-consuming,…

eess.IV2021★ 47 cited

Neural network-based image reconstruction in swept-source optical coherence tomography using undersampled spectral data

Yijie Zhang, Tairan Liu, Manmohan Singh +4

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning…

eess.IV2020★ 323 cited

Deep learning-based transformation of the H&E stain into special stains

Kevin de Haan, Yijie Zhang, Jonathan E. Zuckerman +11

Pathology is practiced by visual inspection of histochemically stained slides. Most commonly, the hematoxylin and eosin (H&E) stain is used in the diagnostic workflow and it is the…

eess.IV2020★ 165 cited

Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue

Yijie Zhang, Kevin de Haan, Yair Rivenson +3

Histological staining is a vital step used to diagnose various diseases and has been used for more than a century to provide contrast to tissue sections, rendering the tissue const…