2 citations · 2 across the 3 of their papers we have counts for
4 papers
Is Retrieval All You Need? Assessment and Emergence of Novelty in Protein Structure Generation
Tongyue Xu, Yijie Zhang, Mutian He +4
Protein backbone generation models are often credited with exploring novel fold space based solely on low full-chain similarity to known proteins, yet this cannot distinguish a gen…
dyAb: Flow Matching for Flexible Antibody Design with AlphaFold-driven Pre-binding Antigen
Cheng Tan, Yijie Zhang, Zhangyang Gao +6
The development of therapeutic antibodies heavily relies on accurate predictions of how antigens will interact with antibodies. Existing computational methods in antibody design of…
Efficiently Predicting Protein Stability Changes Upon Single-point Mutation with Large Language Models
Yijie Zhang, Zhangyang Gao, Cheng Tan +1
Predicting protein stability changes induced by single-point mutations has been a persistent challenge over the years, attracting immense interest from numerous researchers. The ab…
RDesign: Hierarchical Data-efficient Representation Learning for Tertiary Structure-based RNA Design
Cheng Tan, Yijie Zhang, Zhangyang Gao +4
While artificial intelligence has made remarkable strides in revealing the relationship between biological macromolecules' primary sequence and tertiary structure, designing RNA se…