253 citations · 415 across the 23 of their papers we have counts for
27 papers
Recursive Reward Improvement via Adversarial Meta-Prompt Evolution
Wei Dai, Qianchu Liu, Guanghui Qin +4
Recursive Self-Improvement (RSI) has gained wide attention for its ability to work with limited data. In a proposer-solver loop, a proposer model writes training tasks and a solver…
HERO: Harnessing Evidence for Test-time Refinement and Prompt Optimization in Program Generation
Mingyu Lu, Timothy Ossowski, Tristan Naumann +2
Harness optimization improves LLMs by refining reusable prompts and scaffolding, yet requires further adaptation for program generation tasks such as text-to-SQL and text-to-Python…
Reinforcement Learning over Patient Trajectories for Clinical Reasoning in EHR Foundation Models
Yuxin Xiao, Sheng Zhang, Chandan Singh +4
Electronic health record (EHR) foundation models trained on longitudinal patient trajectories have demonstrated strong performance across diverse clinical prediction tasks. However…
Large Language Models are Approximate Survival Estimators
Juan M Zambrano Chaves, Peniel Argaw, Risa Ueno +5
Survival analysis estimates time-to-event outcomes from patient covariates and is widely used for medical risk assessment. Patients seeking prognostic information after a diagnosis…
GigaPath-Flash and GigaTIME-Flash: Efficient Pathology Foundation Models for Whole-Slide and Tumor Microenvironment Analysis
Naoto Usuyama, Jeya Maria Jose Valanarasu, Sicong Yao +27
Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning trans…
HealthAgentBench: A Unified Benchmark Suite of Realistic Agentic Healthcare Environments for Challenging Frontier AI Agents
Qianchu Liu, Sheng Zhang, Guanghui Qin +16
As AI agents become increasingly capable of complex, long-horizon reasoning, rigorous and holistic evaluation is essential for measuring progress toward real-world healthcare appli…
Learning Sparse Visual Representations via Spatial-Semantic Factorization
Theodore Zhengde Zhao, Sid Kiblawi, Jianwei Yang +6
Self-supervised learning (SSL) faces a fundamental conflict between semantic understanding and image reconstruction. High-level semantic SSL (e.g., DINO) relies on global tokens th…
An Efficient Algorithm for Thresholding Monte Carlo Tree Search
Shoma Nameki, Atsuyoshi Nakamura, Junpei Komiyama +1
We introduce the Thresholding Monte Carlo Tree Search problem, in which, given a tree and a threshold , a player must answer whether the root node value of $\mathc…
Scaling medical imaging report generation with multimodal reinforcement learning
Qianchu Liu, Sheng Zhang, Guanghui Qin +10
Frontier models have demonstrated remarkable capabilities in understanding and reasoning with natural-language text, but they still exhibit major competency gaps in multimodal unde…
OctoMed: Data Recipes for State-of-the-Art Multimodal Medical Reasoning
Timothy Ossowski, Sheng Zhang, Qianchu Liu +5
High-quality and carefully curated data is a cornerstone of training medical large language models, as it directly impacts both generalization and robustness to unseen clinical tas…
Be My Eyes: Extending Large Language Models to New Modalities Through Multi-Agent Collaboration
James Y. Huang, Sheng Zhang, Qianchu Liu +5
Large Language Models (LLMs) have demonstrated remarkable capabilities in challenging, knowledge-intensive reasoning tasks. However, extending LLMs to perceive and reason over a ne…
Generative Medical Event Models Improve with Scale
Shane Waxler, Paul Blazek, Davis White +16
Realizing personalized medicine at scale calls for methods that distill insights from longitudinal patient journeys, which can be viewed as a sequence of medical events. Foundation…
BioClinical ModernBERT: A State-of-the-Art Long-Context Encoder for Biomedical and Clinical NLP
Thomas Sounack, Joshua Davis, Brigitte Durieux +7
Encoder-based transformer models are central to biomedical and clinical Natural Language Processing (NLP), as their bidirectional self-attention makes them well-suited for efficien…
X-Reasoner: Towards Generalizable Reasoning Across Modalities and Domains
Qianchu Liu, Sheng Zhang, Guanghui Qin +9
Recent proprietary models (e.g., o3) have begun to demonstrate strong multimodal reasoning capabilities. Yet, most existing open-source research concentrates on training text-only…
Exploring Scaling Laws for EHR Foundation Models
Sheng Zhang, Qin Liu, Naoto Usuyama +3
The emergence of scaling laws has profoundly shaped the development of large language models (LLMs), enabling predictable performance gains through systematic increases in model si…
Med-RLVR: Emerging Medical Reasoning from a 3B base model via reinforcement Learning
Sheng Zhang, Qianchu Liu, Guanghui Qin +2
Reinforcement learning from verifiable rewards (RLVR) has recently gained attention for its ability to elicit self-evolved reasoning capabilitie from base language models without e…
Universal Abstraction: Harnessing Frontier Models to Structure Real-World Data at Scale
Cliff Wong, Sam Preston, Qianchu Liu +22
A significant fraction of real-world patient information resides in unstructured clinical text. Medical abstraction extracts and normalizes key structured attributes from free-text…
BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at once
Theodore Zhao, Yu Gu, Jianwei Yang +12
Biomedical image analysis is fundamental for biomedical discovery in cell biology, pathology, radiology, and many other biomedical domains. Holistic image analysis comprises interd…
Recent Advances, Applications, and Open Challenges in Machine Learning for Health: Reflections from Research Roundtables at ML4H 2023 Symposium
Hyewon Jeong, Sarah Jabbour, Yuzhe Yang +40
The third ML4H symposium was held in person on December 10, 2023, in New Orleans, Louisiana, USA. The symposium included research roundtable sessions to foster discussions between…
Towards a clinically accessible radiology foundation model: open-access and lightweight, with automated evaluation
Juan Manuel Zambrano Chaves, Shih-Cheng Huang, Yanbo Xu +24
The scaling laws and extraordinary performance of large foundation models motivate the development and utilization of such models in biomedicine. However, despite early promising r…
Attribute Structuring Improves LLM-Based Evaluation of Clinical Text Summaries
Zelalem Gero, Chandan Singh, Yiqing Xie +6
Summarizing clinical text is crucial in health decision-support and clinical research. Large language models (LLMs) have shown the potential to generate accurate clinical text summ…
Out of the Ordinary: Spectrally Adapting Regression for Covariate Shift
Benjamin Eyre, Elliot Creager, David Madras +2
Designing deep neural network classifiers that perform robustly on distributions differing from the available training data is an active area of machine learning research. However,…
DocLens: Multi-aspect Fine-grained Evaluation for Medical Text Generation
Yiqing Xie, Sheng Zhang, Hao Cheng +6
Medical text generation aims to assist with administrative work and highlight salient information to support decision-making. To reflect the specific requirements of medical text,…
TRIALSCOPE: A Unifying Causal Framework for Scaling Real-World Evidence Generation with Biomedical Language Models
Javier González, Risa Ueno, Cliff Wong +12
The rapid digitization of real-world data presents an unprecedented opportunity to optimize healthcare delivery and accelerate biomedical discovery. However, these data are often f…