23 citations · 23 across the 1 of their papers we have counts for
6 papers · 1 filter
Resolving the Orientations of and Angular Separation between a Pair of Dipole Emitters
Yiyang Chen, Yuanxin Qiu, Matthew D. Lew
We prove that it is impossible to distinguish two spatially coinciding fluorescent molecules from a single rotating molecule using polarization-sensitive imaging, even if one modul…
Dipole-Spread Function Engineering for 6D Super-Resolution Microscopy
Tingting Wu, Matthew D. Lew
Fluorescent molecules are versatile nanoscale emitters that enable detailed observations of biophysical processes with nanoscale resolution. Because they are well-approximated as e…
Single-molecule orientation localization microscopy II: a performance comparison
Oumeng Zhang, Matthew D. Lew
Various techniques have been developed to measure the 2D and 3D positions and 2D and 3D orientations of fluorescent molecules with improved precision over standard epifluorescence…
Single-molecule orientation localization microscopy I: fundamental limits
Oumeng Zhang, Matthew D. Lew
Precisely measuring the three-dimensional position and orientation of individual fluorophores is challenging due to the substantial photon shot noise in single-molecule experiments…
Quantum limits for precisely estimating the orientation and wobble of dipole emitters
Oumeng Zhang, Matthew D. Lew
Precisely measuring molecular orientation is key to understanding how molecules organize and interact in soft matter, but the maximum theoretical limit of measurement precision has…
Fundamental Limits on Measuring the Rotational Constraint of Single Molecules using Fluorescence Microscopy
Oumeng Zhang, Matthew D. Lew
Optical fluorescence imaging is capable of measuring both the spatial and rotational dynamics of single molecules. However, unavoidable measurement noise will result in inaccurate…