175 citations · 608 across the 24 of their papers we have counts for
24 papers
Pattern Formation in Bioconvection of Thiovulum in a Hele-Shaw Chamber
Trey Johnson, George A. Schaible, Yujia Qi +4
This paper is associated with a video winner of a 2025 American Physical Society's Division of Fluid Dynamics (DFD) Gallery of Fluid Motion Award for work presented at the DFD Gall…
Tissue shape from cell-scale active tensions
Nikolas H. Claussen, Fridtjof Brauns, Boris I. Shraiman
Connecting cell and tissue mechanics is a fundamental challenge in the physics of morphogenesis. Conventional elasticity theory is generally inapplicable: cytoskeletal turnover pre…
Emergent Elasticity and Quasiconformal Flow in Active Solids
Nikolas H. Claussen, Fridtjof Brauns, Boris I. Shraiman
A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governe…
Feedback-controlled mechanics of tissue vertex model: emergent soft elasticity and active yielding
Pengyu Yu, Fridtjof Brauns, M. Cristina Marchetti
Biological tissues exhibit diverse mechanical and rheological behaviors during morphogenesis. While much is known about tissue phase transitions controlled by structural order and…
Proliferating Nematic That Collectively Senses an Anisotropic Substrate
Toshi Parmar, Fridtjof Brauns, Yimin Luo +1
Motivated by recent experiments on growing fibroblasts, we examine the development of nematic order in a colony of elongated cells proliferating on a nematic elastomer substrate. A…
Topology and Kinetic Pathways of Colloidosome Assembly and Disassembly
Raymond Adkins, Joanna Robaszewski, Seungwoo Shin +7
Liquid shells, such as lipid vesicles and soap bubbles, are ubiquitous throughout biology, engineered matter, and everyday life. Their creation and disintegration are defined by a…
Active Solids: Topological Defect Self-Propulsion Without Flow
Fridtjof Brauns, Myles O'Leary, Arthur Hernandez +2
The self-propulsion of +1/2 topological defects is a hallmark of active nematic fluids, where the defects are advected by the flow field they themselves generate. In this paper we…
The 2024 Motile Active Matter Roadmap
Gerhard Gompper, Howard A. Stone, Christina Kurzthaler +29
Activity and autonomous motion are fundamental aspects of many living and engineering systems. Here, the scale of biological agents covers a wide range, from nanomotors, cytoskelet…
A Mean-Field Model for Active Plastic Flow of Epithelial Tissue
Nikolas H. Claussen, Fridtjof Brauns
Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and…
Active assembly and non-reciprocal dynamics of elastic membranes
John Berezney, Sattvic Ray, Itamar Kolvin +6
Equilibrium self-assembly and conventional materials processing techniques fall far short of mimicking dynamic self-actuating processes that are commonplace throughout biology. To…
Learning a conserved mechanism for early neuroectoderm morphogenesis
Matthew Lefebvre, Jonathan Colen, Nikolas Claussen +6
Morphogenesis is the process whereby the body of an organism develops its target shape. The morphogen BMP is known to play a conserved role across bilaterian organisms in determini…
A Geometric Tension Dynamics Model of Epithelial Convergent Extension
Nikolas H. Claussen, Fridtjof Brauns, Boris I. Shraiman
Convergent extension of epithelial tissue is a key motif of animal morphogenesis. On a coarse scale, cell motion resembles laminar fluid flow; yet in contrast to a fluid, epithelia…
Nonreciprocal pattern formation of conserved fields
Fridtjof Brauns, M. Cristina Marchetti
In recent years, nonreciprocally coupled systems have received growing attention. Previous work has shown that the interplay of nonreciprocal coupling and Goldstone modes can drive…
Patterning of morphogenetic anisotropy fields
Zihang Wang, M. Cristina Marchetti, Fridtjof Brauns
Orientational order, encoded in anisotropic fields, plays an important role during the development of an organism. A striking example of this is the freshwater polyp Hydra, where t…
Coarsening and wavelength selection far from equilibrium: a unifying framework based on singular perturbation theory
Henrik Weyer, Fridtjof Brauns, Erwin Frey
Intracellular protein patterns are described by (nearly) mass-conserving reaction-diffusion systems. While these patterns initially form out of a homogeneous steady state due to th…
Bridging scales in a multiscale pattern-forming system
Laeschkir Würthner, Fridtjof Brauns, Grzegorz Pawlik +4
Self-organized pattern formation is vital for many biological processes. Reaction-diffusion models have advanced our understanding of how biological systems develop spatial structu…
Length Regulation Drives Self-Organization in Filament-Motor Mixtures
Moritz Striebel, Fridtjof Brauns, Erwin Frey
Cytoskeletal networks form complex intracellular structures. Here we investigate a minimal model for filament-motor mixtures in which motors act as depolymerases and thereby regula…
Self-organisation of Protein Patterns
Erwin Frey, Fridtjof Brauns
These notes are an account of a series of lectures given at the Les Houches Summer School "Active Matter and Non-equilibrium Statistical Physics" during August and September 2018.
Diffusive coupling of two well-mixed compartments elucidates elementary principles of protein-based pattern formation
Fridtjof Brauns, Jacob Halatek, Erwin Frey
Spatial organization of proteins in cells is important for many biological functions. In general, the nonlinear, spatially coupled models for protein-pattern formation are only acc…
Cytosolic flow induced symmetry breaking in a conceptual polarity model
Manon C Wigbers, Fridtjof Brauns, Ching Yee Leung +1
Important cellular processes, such as cell motility and cell division, are coordinated by cell polarity, which is determined by the non-uniform distribution of certain proteins. Su…
Wavelength selection by interrupted coarsening in reaction-diffusion systems
Fridtjof Brauns, Henrik Weyer, Jacob Halatek +2
Wavelength selection in reaction--diffusion systems can be understood as a coarsening process that is interrupted by counteracting processes at certain wavelengths. We first show t…
Pattern localization to a domain edge
Manon C. Wigbers, Fridtjof Brauns, Tobias Hermann +1
The formation of protein patterns inside cells is generically described by reaction-diffusion models. The study of such systems goes back to Turing, who showed how patterns can eme…
Phase-space geometry of mass-conserving reaction-diffusion dynamics
Fridtjof Brauns, Jacob Halatek, Erwin Frey
Experimental studies of protein-pattern formation have stimulated new interest in the dynamics of reaction-diffusion systems. However, a comprehensive theoretical understanding of…
Self-organization principles of intracellular pattern formation
Jacob Halatek, Fridtjof Brauns, Erwin Frey
Dynamic patterning of specific proteins is essential for the spatiotemporal regulation of many important intracellular processes in procaryotes, eucaryotes, and multicellular organ…