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20182026
most citedSelf-organization principles of intracellular pattern formation

175 citations · 608 across the 24 of their papers we have counts for

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9 papers · 1 filter

physics.bio-ph2024★ 1 cited

Learning a conserved mechanism for early neuroectoderm morphogenesis

Matthew Lefebvre, Jonathan Colen, Nikolas Claussen +6

Morphogenesis is the process whereby the body of an organism develops its target shape. The morphogen BMP is known to play a conserved role across bilaterian organisms in determini…

physics.bio-ph2023★ 35 cited

A Geometric Tension Dynamics Model of Epithelial Convergent Extension

Nikolas H. Claussen, Fridtjof Brauns, Boris I. Shraiman

Convergent extension of epithelial tissue is a key motif of animal morphogenesis. On a coarse scale, cell motion resembles laminar fluid flow; yet in contrast to a fluid, epithelia…

physics.bio-ph2022★ 39 cited

Patterning of morphogenetic anisotropy fields

Zihang Wang, M. Cristina Marchetti, Fridtjof Brauns

Orientational order, encoded in anisotropic fields, plays an important role during the development of an organism. A striking example of this is the freshwater polyp Hydra, where t…

physics.bio-ph2021★ 45 cited

Bridging scales in a multiscale pattern-forming system

Laeschkir Würthner, Fridtjof Brauns, Grzegorz Pawlik +4

Self-organized pattern formation is vital for many biological processes. Reaction-diffusion models have advanced our understanding of how biological systems develop spatial structu…

physics.bio-ph2021★ 2 cited

Length Regulation Drives Self-Organization in Filament-Motor Mixtures

Moritz Striebel, Fridtjof Brauns, Erwin Frey

Cytoskeletal networks form complex intracellular structures. Here we investigate a minimal model for filament-motor mixtures in which motors act as depolymerases and thereby regula…

physics.bio-ph2020★ 3 cited

Self-organisation of Protein Patterns

Erwin Frey, Fridtjof Brauns

These notes are an account of a series of lectures given at the Les Houches Summer School "Active Matter and Non-equilibrium Statistical Physics" during August and September 2018.

physics.bio-ph2020

Cytosolic flow induced symmetry breaking in a conceptual polarity model

Manon C Wigbers, Fridtjof Brauns, Ching Yee Leung +1

Important cellular processes, such as cell motility and cell division, are coordinated by cell polarity, which is determined by the non-uniform distribution of certain proteins. Su…

physics.bio-ph2019★ 23 cited

Pattern localization to a domain edge

Manon C. Wigbers, Fridtjof Brauns, Tobias Hermann +1

The formation of protein patterns inside cells is generically described by reaction-diffusion models. The study of such systems goes back to Turing, who showed how patterns can eme…

physics.bio-ph2018★ 175 cited

Self-organization principles of intracellular pattern formation

Jacob Halatek, Fridtjof Brauns, Erwin Frey

Dynamic patterning of specific proteins is essential for the spatiotemporal regulation of many important intracellular processes in procaryotes, eucaryotes, and multicellular organ…