activity
20202024
most citedA neutral comparison of statistical methods for time-to-event analyses under non-proportional hazards

2 citations · 2 across the 5 of their papers we have counts for

collaborators

5 papers

math.ST2024

A studentized permutation test in group sequential designs

Long-Hao Xu, Tobias Mütze, Frank Konietschke +1

In group sequential designs, where several data looks are conducted for early stopping, we generally assume the vector of test statistics from the sequential analyses follows (at l…

stat.AP2024

Survival analysis for AdVerse events with VarYing follow-up times (SAVVY): summary of findings and a roadmap for the future of safety analyses in clinical trials

Kaspar Rufibach, Jan Beyersmann, Tim Friede +2

The SAVVY project aims to improve the analyses of adverse events (AEs) in clinical trials through the use of survival techniques appropriately dealing with varying follow-up times…

stat.ME2023

Subgroup identification using individual participant data from multiple trials on low back pain

Cynthia Huber, Tim Friede

Model-based recursive partitioning (MOB) and its extension, metaMOB, are potent tools for identifying subgroups with differential treatment effects. In the metaMOB approach random…

stat.ME2023★ 2 cited

A neutral comparison of statistical methods for time-to-event analyses under non-proportional hazards

Florian Klinglmüller, Tobias Fellinger, Franz König +10

While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non…

q-bio.QM2020

Efficient adaptive designs for clinical trials of interventions for COVID-19

Nigel Stallard, Lisa Hampson, Norbert Benda +14

The COVID-19 pandemic has led to an unprecedented response in terms of clinical research activity. An important part of this research has been focused on randomized controlled clin…