144 citations · 483 across the 12 of their papers we have counts for
12 papers
Societal self-regulation induces complex infection dynamics and chaos
Joel Wagner, Simon Bauer, Sebastian Contreras +3
Classically, endemic infectious diseases are expected to display relatively stable, predictable infection dynamics. Accordingly, basic disease models such as the susceptible-infect…
Model-based assessment of sampling protocols for infectious disease genomic surveillance
Sebastian Contreras, Karen Y. Oróstica, Anamaria Daza-Sanchez +8
Genomic surveillance of infectious diseases allows monitoring circulating and emerging variants and quantifying their epidemic potential. However, due to the high costs associated…
Impact of the Euro 2020 championship on the spread of COVID-19
Jonas Dehning, Sebastian B. Mohr, Sebastian Contreras +5
Large-scale events like the UEFA Euro~2020 football (soccer) championship offer a unique opportunity to quantify the impact of gatherings on the spread of COVID-19, as the number a…
Interplay between risk perception, behaviour, and COVID-19 spread
Philipp Dönges, Joel Wagner, Sebastian Contreras +9
Pharmaceutical and non-pharmaceutical interventions (NPIs) have been crucial for controlling COVID-19. They are complemented by voluntary health-protective behaviour, building a co…
The winter dilemma
Sebastian Contreras, Philipp Dönges, Joel Wagner +8
With winter coming in the northern hemisphere, disadvantageous seasonality of SARS-CoV-2 requires high immunity levels in the population or increasing non-pharmaceutical interventi…
Mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants
Karen Y. Oróstica, Sebastian Contreras, Sebastian B. Mohr +12
The emergence of SARS-CoV-2 variants of concern endangers the long-term control of COVID-19, especially in countries with limited genomic surveillance. In this work, we explored ge…
Relaxing restrictions at the pace of vaccination increases freedom and guards against further COVID-19 waves
Simon Bauer, Sebastian Contreras, Jonas Dehning +5
Mass vaccination offers a promising exit strategy for the COVID-19 pandemic. However, as vaccination progresses, demands to lift restrictions increase, despite most of the populati…
Low case numbers enable long-term stable pandemic control without lockdowns
Sebastian Contreras, Jonas Dehning, Sebastian B. Mohr +3
The traditional long-term solutions for epidemic control involve eradication or population immunity. Here, we analytically derive the existence of a third viable solution: a stable…
Combination of digital signal processing and assembled predictive models facilitates the rational design of proteins
David Medina-Ortiz, Sebastian Contreras, Juan Amado-Hinojosa +4
Predicting the effect of mutations in proteins is one of the most critical challenges in protein engineering; by knowing the effect a substitution of one (or several) residues in t…
The challenges of containing SARS-CoV-2 via test-trace-and-isolate
Sebastian Contreras, Jonas Dehning, Matthias Loidolt +7
Without a cure, vaccine, or proven long-term immunity against SARS-CoV-2, test-trace-and-isolate (TTI) strategies present a promising tool to contain its spread. For any TTI strate…
Statistically-based methodology for revealing real contagion trends and correcting delay-induced errors in the assessment of COVID-19 pandemic
Sebastián Contreras, Juan Pablo Biron-Lattes, H. Andrés Villavicencio +3
COVID-19 pandemic has reshaped our world in a timescale much shorter than what we can understand. Particularities of SARS-CoV-2, such as its persistence in surfaces and the lack of…
A multi-group SEIRA model for the spread of COVID-19 among heterogeneous populations
Sebastian Contreras, H. Andres Villavicencio, David Medina-Ortiz +2
The outbreak and propagation of COVID-19 have posed a considerable challenge to modern society. In particular, the different restrictive actions taken by governments to prevent the…