activity
20192026
most citedReview of the mechanisms of SARS-CoV-2 evolution and transmission

12 citations · 74 across the 25 of their papers we have counts for

collaborators

26 papers

math.AT2026

Geometry-Induced Hodge Stars on Rips and Dowker--Rips Complexes

Jiahui Chen, Sebastian Wilcox

The Vietoris--Rips complex , the Dowker complex , and its flagified Dowker--Rips variant are…

q-bio.PE2025

Dimensionality reduction for k-means clustering of large-scale influenza mutation datasets

Emilee Walden, Jiahui Chen, Guo-Wei Wei

Viral mutations pose significant threats to public health by increasing infectivity, strengthening vaccine resistance, and altering disease severity. To track these evolving patter…

q-bio.QM2024

Drug Resistance Predictions Based on a Directed Flag Transformer

Dong Chen, Gengzhuo Liu, Hongyan Du +6

The continuous evolution of the SARS-CoV-2 virus poses a significant challenge to global public health. Of particular concern is the potential resistance to the widely prescribed d…

q-bio.BM2023

Integration of persistent Laplacian and pre-trained transformer for protein solubility changes upon mutation

JunJie Wee, Jiahui Chen, Kelin Xia +1

Protein mutations can significantly influence protein solubility, which results in altered protein functions and leads to various diseases. Despite of tremendous effort, machine le…

q-bio.QM2023

Persistent topological Laplacian analysis of SARS-CoV-2 variants

Xiaoqi Wei, Jiahui Chen, Guo-Wei Wei

Topological data analysis (TDA) is an emerging field in mathematics and data science. Its central technique, persistent homology, has had tremendous success in many science and eng…

q-bio.PE2022★ 1 cited

Emerging dominant SARS-CoV-2 variants

Jiahui Chen, Rui Wang, Yuta Hozumi +4

Accurate and reliable forecasting of emerging dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants enables policymakers and vaccine makers to get prepared…