12 citations · 74 across the 25 of their papers we have counts for
8 papers · 1 filter
HERMES: Persistent spectral graph software
Rui Wang, Rundong Zhao, Emily Ribando-Gros +3
Persistent homology (PH) is one of the most popular tools in topological data analysis (TDA), while graph theory has had a significant impact on data science. Our earlier work intr…
Prediction and mitigation of mutation threats to COVID-19 vaccines and antibody therapies
Jiahui Chen, Kaifu Gao, Rui Wang +1
Antibody therapeutics and vaccines are among our last resort to end the raging COVID-19 pandemic. They, however, are prone to over 5,000 mutations on the spike (S) protein uncovere…
Characterizing SARS-CoV-2 mutations in the United States
Rui Wang, Jiahui Chen, Kaifu Gao +3
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been mutating since it was first sequenced in early January 2020. The genetic variants have developed into a fe…
Decoding asymptomatic COVID-19 infection and transmission
Rui Wang, Yuta Hozumi, Changchuan Yin +1
Coronavirus disease 2019 (COVID-19) is a continuously devastating public health and the world economy. One of the major challenges in controlling the COVID-19 outbreak is its asymp…
Review of COVID-19 Antibody Therapies
Jiahui Chen, Kaifu Gao, Rui Wang +2
Under the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient and specific therapies are urgently needed. Compared with traditional small-molecular dru…
Mutations strengthened SARS-CoV-2 infectivity
Jiahui Chen, Rui Wang, Menglun Wang +1
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity is a major concern in coronavirus disease 2019 (COVID-19) prevention and economic reopening. However, rigor…
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 92 crystal structures
Duc D Nguyen, Kaifu Gao, Jiahui Chen +2
Currently, there is no effective antiviral drugs nor vaccine for coronavirus disease 2019 (COVID-19) caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to its hig…
Repositioning of 8565 existing drugs for COVID-19
Kaifu Gao, Duc Duy Nguyen, Jiahui Chen +2
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected near 5 million people and led to over 0.3 milli…