14 citations · 14 across the 2 of their papers we have counts for
5 papers
New views of old proteins: clarifying the enigmatic proteome
Participants in a NIH Workshop on Functional, Integrative Proteomics, : +20
All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition…
Analyzing ribosome remodeling in health and disease
Aleksandra A. Petelski, Nikolai Slavov
regulation largely unexplored, in part due to methodological limitations. Indeed, we review evidence demonstrating that commonly used methods, such as transcriptomics, are inadequa…
Single-cell protein analysis by mass-spectrometry
Nikolai Slavov
Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughp…
Mass-spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation
Bogdan Budnik, Ezra Levy, Guillaume Harmange +1
Cellular heterogeneity is important to biological processes, including cancer and development. However, proteome heterogeneity is largely unexplored because of the limitations of e…
Routinely quantifying single cell proteomes: A new age in quantitative biology and medicine
Harrison Specht, Nikolai Slavov
Many pressing medical challenges - such as diagnosing disease, enhancing directed stem cell differentiation, and classifying cancers - have long been hindered by limitations in our…