887 citations · 2k across the 14 of their papers we have counts for
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q-bio.QM2022★ 88 cited
Sampling the proteome by emerging single-molecule and mass-spectrometry methods
Michael J. MacCoss, Javier Alfaro, Meni Wanunu +2
Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications i…
q-bio.OT2022★ 179 cited
Initial recommendations for performing, benchmarking, and reporting single-cell proteomics experiments
Laurent Gatto, Ruedi Aebersold, Juergen Cox +18
Analyzing proteins from single cells by tandem mass spectrometry (MS) has become technically feasible. While such analysis has the potential to accurately quantify thousands of pro…