93 citations · 95 across the 4 of their papers we have counts for
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q-bio.QM2018★ 2 cited
Estimating Cellular Goals from High-Dimensional Biological Data
Laurence Yang, Michael A. Saunders, Jean-Christophe Lachance +2
Optimization-based models have been used to predict cellular behavior for over 25 years. The constraints in these models are derived from genome annotations, measured macro-molecul…
q-bio.QM2017★ 93 cited
Creation and analysis of biochemical constraint-based models: the COBRA Toolbox v3.0
Laurent Heirendt, Sylvain Arreckx, Thomas Pfau +52
COnstraint-Based Reconstruction and Analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental data and quantitative prediction of physico…