20 citations · 48 across the 10 of their papers we have counts for
11 papers
SARS-CoV-2 mortality in blacks and temperature-sensitivity to an angiotensin-2 receptor blocker
Donald R. Forsdyke
Tropical climates provoke adaptations in skin pigmentation and in mechanisms controlling the volume, salt-content and pressure of body fluids. For many whose distant ancestors move…
Success of Alignment-Free Oligonucleotide (k-mer) Analysis Confirms Relative Importance of Genomes not Genes in Speciation and Phylogeny
Donald R. Forsdyke
The utility of DNA sequence substrings (k-mers) in alignment-free phylogenetic classification, including that of bacteria and viruses, is increasingly recognized. However, its biol…
Confirmation that T cell receptor activation is digital, not analog. Hence individual T cell cytolytic capacity is independent of initial stimulation strength
Donald R. Forsdyke
Whether a sub-optimum lymphocyte stimulus is achieved by lowering ligand concentration, or decreasing its affinity, initial TCR activation responses are likely to be digital. We no…
Shift in Nomenclature not Thesis: Innate Immune Memory, Pathogen Dose and Opsonins
Donald R. Forsdyke
Recent writings on "innate immune memory" or "trained immunity," and on "hormetic responses," herald reinvigoration of an important research area with early 20th century roots. How…
When few survive to tell the tale: thymus and gonad as auditioning organs: historical overview
Donald Roy Forsdyke
Unlike other organs, the thymus and gonads generate non-uniform cell populations, many members of which perish, and a few survive. While it is recognized that thymic cells are 'aud…
When acting as a reproductive barrier for sympatric speciation, hybrid sterility can only be primary
Donald R. Forsdyke
In many animals parental gametes unite to form a zygote that develops into an adult with gonads that, in turn, produce gametes. Interruption of this germinal cycle by prezygotic or…
Speciation: Goldschmidt's Heresy, Once Supported by Gould and Dawkins, is Again Reinstated
Donald R. Forsdyke
The view that the initiation of branching into two sympatric species may not require natural selection emerged in Victorian times (Fleeming Jenkin, George Romanes, William Bateson)…
Elusive preferred hosts or nucleic acid level selection? A commentary on: Evolutionary interpretations of mycobacteriophage biodiversity and host-range through the analysis of codon usage bias (Esposito et al. 2016)
Donald R. Forsdyke
While confirming the long held view that viruses do not closely imitate the use of their host's codon catalogue, Esposito and coworkers nevertheless consider it surprising that, de…
'A Vehicle of Symbols and Nothing More.' George Romanes, Theory of Mind, Information, and Samuel Butler
Donald R. Forsdyke
Today's 'theory of mind' (ToM) concept is rooted in the distinction of nineteenth century philosopher William Clifford between 'objects' that can be directly perceived, and 'ejects…
Long-Term Memory: Scaling of Information to Brain Size
Donald R. Forsdyke
The material bases of information - paper, computer discs - usually scale with information quantity. Large quantities of information usually require large material bases. Conventio…
Role of HIV RNA structure in recombination and speciation: romping in purine A, keeps HTLV away
Donald R. Forsdyke
Extreme enrichment of the human immunodeficiency virus (HIV-1) RNA genome for the purine A parallels the mild purine-loading of the RNAs of most organisms. This should militate aga…