174 citations · 650 across the 14 of their papers we have counts for
16 papers
Robust retrieval of dynamic sequences through interaction modulation
Lukas Herron, Pablo Sartori, BingKan Xue
Many biological systems dynamically rearrange their components through a sequence of configurations in order to perform their functions. Such dynamic processes have been studied us…
Ciliary beating patterns map onto a low-dimensional behavioral space that accords with a simple mechanochemical model
Veikko Geyer, Jonathon Howard, Pablo Sartori
Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between f…
Towards a theory of assembly of protein complexes: lessons from equilibrium statistical physics
Pablo Sartori, Stanislas Leibler
Cellular functions are established through biological evolution, but are constrained by the laws of physics. For instance, the physics of protein folding limits the lengths of cell…
Scaling behaviour of non-equilibrium planar -atic spin systems under weak fluctuations
Pablo Sartori, Chiu Fan Lee
Starting from symmetry considerations, we derive the generic hydrodynamic equation of non-equilibrium spin systems with -atic symmetry under weak fluctuations. Through a sy…
Effect of curvature and normal forces on motor regulation of cilia
Pablo Sartori
Cilia are ubiquitous organelles involves in eukaryotic motility. They are long, slender, and motile protrusions from the cell body. They undergo active regular oscillatory beating…
Geometry of environment-to-phenotype mapping: Unifying adaptation strategies in varying environments
BingKan Xue, Pablo Sartori, Stanislas Leibler
Biological organisms exhibit diverse strategies for adapting to varying environments. For example, a population of organisms may express the same phenotype in all environments (`un…
On the nonequilibrium entropy of large and small systems
Sheldon Goldstein, David A. Huse, Joel L. Lebowitz +1
Thermodynamics makes definite predictions about the thermal behavior of macroscopic systems in and out of equilibrium. Statistical mechanics aims to derive this behavior from the d…
Protocols for copying and proofreading in template-assisted polymerization
Simone Pigolotti, Pablo Sartori
We discuss how information encoded in a template polymer can be stochastically copied into a copy polymer. We consider four different stochastic copy protocols of increasing comple…
Beat regulation in twisted axonemes
Pablo Sartori, Veikko Geyer, Jonathon Howard +1
Cilia and flagella are hairlike organelles that propel cells through fluid. The active motion of the axoneme, the motile structure inside cilia and flagella, is powered by molecula…
Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella
Pablo Sartori, Veikko Geyer, Andre Scholich +2
Axonemal dyneins are the molecular motors responsible for the beating of cilia and flagella. These motors generate sliding forces between adjacent microtubule doublets within the a…
The free energy cost of reducing noise while maintaining a high sensitivity
Pablo Sartori, Yuhai Tu
Living systems need to be highly responsive, and also to keep fluctuations low. These goals are incompatible in equilibrium systems due to the Fluctuation Dissipation Theorem (FDT)…
Thermodynamics of Error Correction
Pablo Sartori, Simone Pigolotti
Information processing at the molecular scale is limited by thermal fluctuations. This can cause undesired consequences in copying information since thermal noise can lead to error…
Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs
V. Mukundan, P. Sartori, V. F. Geyer +2
The bending of cilia and flagella is driven by forces generated by dynein motor proteins. These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskelet…
Thermodynamic costs of information processing in sensory adaption
Pablo Sartori, Léo Granger, Chiu Fan Lee +1
Biological sensory systems react to changes in their surroundings. They are characterized by fast response and slow adaptation to varying environmental cues. Insofar as sensory ada…
Kinetic vs. energetic discrimination in biological copying
Pablo Sartori, Simone Pigolotti
We study stochastic copying schemes in which discrimination between a right and a wrong match is achieved via different kinetic barriers or different binding energies of the two ma…
Noise Filtering Strategies of Adaptive Signaling Networks: The Case of E. Coli Chemotaxis
Pablo Sartori, Yuhai Tu
Two distinct mechanisms for filtering noise in an input signal are identified in a class of adaptive sensory networks. We find that the high frequency noise is filtered by the outp…