The Effects of Stacking on the Configurations and Elasticity of Single Stranded Nucleic Acids

Abstract

Stacking interactions in single stranded nucleic acids give rise to configurations of an annealed rod-coil multiblock copolymer. Theoretical analysis identifies the resulting signatures for long homopolynucleotides: A non monotonous dependence of size on temperature, corresponding effects on cyclization and a plateau in the extension force law. Explicit numerical results for poly(dA) and poly(rU) are presented.

arXiv comment4 pages and 2 figures. Accepted in Phys. Rev. E Rapid Comm

References in corpus (2)

• The Extension of Rod-Coil Multiblock Copolymers and the Effect of the Helix-Coil Transition
• On the Extension Behavior of Helicogenic Polypeptides

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• Sequence-dependent Three Interaction Site (TIS) Model for Single and Double-stranded DNA
• Stretching of a single-stranded DNA: Evidence for structural transition
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• Sugar-Pucker Force-Induced Transition in Single-Stranded~DNA