137 citations · 458 across the 6 of their papers we have counts for
6 papers
Brush Effects on DNA Chips: Thermodynamics, Kinetics and Design Guidlines
A. Halperin, A. Buhot, E. B. Zhulina
In biology experiments, oligonucleotide microarrays are contacted with a solution of long nucleic acid (NA) targets. The hybridized probes thus carry long tails. When the surface d…
The Effects of Stacking on the Configurations and Elasticity of Single Stranded Nucleic Acids
A. Buhot, A. Halperin
Stacking interactions in single stranded nucleic acids give rise to configurations of an annealed rod-coil multiblock copolymer. Theoretical analysis identifies the resulting signa…
Sensitivity, Specificity and the Hybridization Isotherms of DNA Chips
A. Halperin, A. Buhot, E. B. Zhulina
Competitve hybridization, at the surface and in the bulk, lowers the sensitivity of DNA chips. Competitive surface hybridization occurs when different targets can hybridize with th…
On the Helix-Coil transition in grafted chains
A. Buhot, A. Halperin
The helix-coil transition is modified by grafting to a surface. This modification is studied for short peptides capable of forming -helices. Three factors are involved: (i) the…
The Extension of Rod-Coil Multiblock Copolymers and the Effect of the Helix-Coil Transition
A. Buhot, A. Halperin
The extension elasticity of rod-coil mutliblock copolymers is analyzed for two experimentally accessible situations. In the quenched case, when the architecture is fixed by the syn…
Early Stages of Homopolymer Collapse
A. Halperin, Paul M. Goldbart
Interest in the protein folding problem has motivated a wide range of theoretical and experimental studies of the kinetics of the collapse of flexible homopolymers. In this Paper a…