Renewal processes and fluctuation analysis of molecular motor stepping

Abstract

We model the dynamics of a processive or rotary molecular motor using a renewal processes, in line with the work initiated by Svoboda, Mitra and Block. We apply a functional technique to compute different types of multiple-time correlation functions of the renewal process, which have applications to bead-assay experiments performed both with processive molecular motors, such as myosin V and kinesin, and rotary motors, such as F1-ATPase.

References in corpus (6)

• Energy Transduction of Isothermal Ratchets: Generic Aspects and Specific Examples Close to and Far from Equilibrium
• A Simple Kinetic Model Describes the Processivity of Myosin-V
• Dynamics of Molecular Motors and Polymer Translocation with Sequence Heterogeneity
• Elastic lever arm model for myosin V
• Detachment of molecular motors under tangential loading
• Master Equation Approach to Molecular Motors

Cited by in corpus (5)

• Dwell time symmetry in random walks and molecular motors
• Transitions in the ergodicity of subrecoil-laser-cooled gases
• Stepping and crowding of molecular motors: statistical kinetics from an exclusion process perspective
• Dynamics of non-Markovian exclusion processes
• Gas of sub-recoiled laser cooled atoms described by infinite ergodic theory