Local, mm-scale ${}^1$H magnetic resonance imaging using atomic vapors

Abstract

We demonstrate a practical and sensitive low-field approach to magnetic resonance imaging (MRI) of $\mu$L-scale samples using an optically pumped magnetometer (OPM). Using a simple setup where a commercial OPM is placed directly adjacent to a sample, without intermediary signal-pickup coils, we perform one- and two-dimensional imaging with a >1 cm field of view and sub-mm Fourier-limited resolution at 10 $\mu$T, near Earth's field. This enables (i) high-throughput, low-field MRI of fluidic and tissue samples, and (ii) a quantitative benchmark of the sensitive volume surrounding the OPM.

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