Far-field Super-resolution Chemical Microscopy
arXiv:2305.10658 · doi:10.1038/s41377-023-01182-7
Abstract
Far-field chemical microscopy providing molecular electronic or vibrational fingerprint information opens a new window for the study of three-dimensional biological, material, and chemical systems. Chemical microscopy provides a nondestructive way of chemical identification without exterior labels. However, the diffraction limit of optics hindered it from discovering more details under the resolution limit. Recent development of super-resolution techniques gives enlightenment to open this door behind far-field chemical microscopy. Here, we review recent advances that have pushed the boundary of far-field chemical microscopy in terms of spatial resolution. We further highlight applications in biomedical research, material characterization, environmental study, cultural heritage conservation, and integrated chip inspection.
arXiv comment34 pages, 8 figures,1 table
References in corpus (10)
- The optical microscopy with virtual image breaks a record: 50-nm resolution imaging is demonstrated
- Imaging with quantum states of light
- Photothermal heterodyne imaging of individual nonfluorescent nanoclusters and nanocrystals
- Structured illumination microscopy using a photonic chip
- High-speed in vitro intensity diffraction tomography
- Label-free biochemical quantitative phase imaging with mid-infrared photothermal effect
- Refractive index tomography with structured illumination
- Bond-Selective Intensity Diffraction Tomography
- Quantitative phase imaging with molecular vibrational sensitivity
- Scalable universal tunable virtual-wavevector spatial frequency shift (TVSFS) super-resolution imaging