Alignment interactions drive structural transitions in biological tissues
arXiv:2107.00523 · doi:10.1103/PhysRevE.104.044606
Abstract
Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open question. We investigate the effect of a feedback that tends to align the cell crawling direction with cell elongation in a biological tissue model. We find that the alignment interaction promotes nematic patterns in the fluid phase that eventually undergo a non-equilibrium phase transition into a quasi-hexagonal solid. Meanwhile, highly asymmetric cells do not undergo the liquid-to-solid transition for any value of the alignment coupling. In this regime, the dynamics of cell centers and shape fluctuation show features typical of glassy systems.
References in corpus (32)
- Collective motion
- Theoretical perspective on the glass transition and amorphous materials
- Athermal Phase Separation of Self-Propelled Particles with no Alignment
- Dynamical heterogeneities in a supercooled Lennard-Jones liquid
- A density-independent glass transition in biological tissues
- Motility-driven glass and jamming transitions in biological tissues
- How far from equilibrium is active matter?
- Physical Models of Collective Cell Migration
- Active Jamming: Self-propelled soft particles at high density
- Anomalous dynamics of cell migration
- Energy barriers govern glassy dynamics in tissues
- Multidimensional Stationary Probability Distribution for Interacting Active Particles
- Generalized energy equipartition in harmonic oscillators driven by active baths
- Anisotropy links cell shapes to tissue flow during convergent extension
- Nonequilibrium glassy dynamics of self-propelled hard disks
- Emergence of active nematic behaviour in monolayers of isotropic cells
- Dense active matter model of motion patterns in confluent cell monolayers
- Fundamental differences between glassy dynamics in two and three dimensions
- A geometrically controlled rigidity transition in a model for confluent 3D tissues
- Glassy dynamics of athermal self-propelled particles: Computer simulations and a nonequilibrium microscopic theory
- Clustering and heterogeneous dynamics in a kinetic Monte-Carlo model of self-propelled hard disks
- Activity controls fragility: A Random First Order Transition Theory for an active glass
- Soft yet sharp interfaces in a vertex model of confluent tissue
- Anomalous glassy dynamics in simple models of dense biological tissue
- Dynamical patterns in active nematics on a sphere
- Role of cell deformability in the two-dimensional melting of biological tissues
- Tractions and stress fibers control cell shape and rearrangements in collective cell migration
- Critical Phenomena in Active Matter
- Theory and simulation for equilibrium glassy dynamics in cellular Potts model of confluent biological tissue
- Coordinated tractions increase the size of a collectively moving pack in a cell monolayer
- Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues
- Statistical properties of 3D cell geometry from 2D slices