activity
20182025
most citedElectrostatic complementarity at the interface drives transient protein-protein interactions

58 citations · 205 across the 15 of their papers we have counts for

collaborators

15 papers

physics.optics2025

Emergent learning: neuromorphic photonic computing with accelerated training

Sara Peña-Gutiérrez, Giorgio Gosti, Hongsheng Chen +2

Emergent learning transforms a disordered optical medium into a photonic device capable of storage, recognition, and classification of arbitrary memory patterns. First, we show tha…

q-bio.CB2025

A mother-machine microfluidic device for non-adherent mammalian cells reveals the population growth strategies

Simone Scalise, Giovanna Peruzzi, Davide Caprini +3

We develop a mother machine-like microfluidic device specifically designed to track the proliferation of T-cells via live-cell microscopy. Although numerous microfluidic setups hav…

q-bio.CB2025

Rosette formations as symmetry-breaking events: theory and experiment

Mattia Miotto, Giorgio Gosti, Maria Rosito +6

Multicellular rosettes are observed in different situations such as morphogenesis, wound healing, and cancer progression. While some molecular insights have been gained to explain…

q-bio.CB2024★ 1 cited

Robust assessment of asymmetric division in colon cancer cells

Domenico Caudo, Chiara Giannattasio, Simone Scalise +6

Asymmetric partition of fate determinants during cell division is a hallmark of cell differentiation. Recent work suggested that such a mechanism is hijacked by cancer cells to inc…

q-bio.CB2024★ 4 cited

Probing leukemia cells behavior under starvation

Simone Scalise, Giorgio Gosti, Giancarlo Ruocco +2

The ability of a cancer cell population to achieve heterogeneity in their phenotype distributions offers advantages in tumor invasiveness and drug resistance. Studying the mechanis…

cond-mat.dis-nn2024

Evidence of Scaling Regimes in the Hopfield Dynamics of Whole Brain Model

Giorgio Gosti, Sauro Succi, Giancarlo Ruocco

It is shown that a Hopfield recurrent neural network exhibits a scaling regime, whose specific exponents depend on the number of parcels used and the decay length of the coupling s…

cond-mat.dis-nn2023

Photonic Stochastic Emergent Storage: Exploiting Scattering-intrinsic Patterns for Programmable Deep Classification

Marco Leonetti, Giorgio Gosti, Giancarlo Ruocco

Disorder is a pervasive characteristic of natural systems, offering a wealth of non-repeating patterns. In this study, we present a novel storage method that harnesses naturally-oc…

q-bio.CB2023

Determining cancer cells division strategy

Mattia Miotto, Simone Scalise, Marco Leonetti +3

Heterogeneity in the size distribution of cancer cell populations has been recently linked to drug resistance and invasiveness. However, despite many progresses have been made in u…

q-bio.BM2022★ 58 cited

Electrostatic complementarity at the interface drives transient protein-protein interactions

Greta Grassmann, Lorenzo Di Rienzo, Giorgio Gosti +4

Understanding the molecular mechanisms driving the binding between bio-molecules is a crucial challenge in molecular biology. In this respect, characteristics like the preferential…

physics.bio-ph2021

Prediction of gene expression time series and structural analysis of gene regulatory networks using recurrent neural networks

Michele Monti, Jonathan Fiorentino, Edoardo Milanetti +2

Methods for time series prediction and classification of gene regulatory networks (GRNs) from gene expression data have been treated separately so far. The recent emergence of atte…

physics.bio-ph2021

New algorithm to determine a minimal representation of the molecular surface

Greta Grassmann, Mattia Miotto, Lorenzo Di Rienzo +3

Most proteins perform their biological function by interacting with one or more molecular partners. In this respect, characterizing the features of the molecular surface, especiall…

cond-mat.soft2021★ 13 cited

Alignment interactions drive structural transitions in biological tissues

Matteo Paoluzzi, Luca Angelani, Giorgio Gosti +3

Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open…

q-bio.PE2020★ 43 cited

Does blood type affect the COVID-19 infection pattern?

Mattia Miotto, Lorenzo Di Rienzo, Giorgio Gosti +2

Among the many aspects that characterize the COVID-19 pandemic, two seem particularly challenging to understand: (i) the great geographical differences in the degree of virus conta…

physics.bio-ph2020★ 52 cited

In-Silico evidence for two receptors based strategy of SARS-CoV-2

Edoardo Milanetti, Mattia Miotto, Lorenzo Di Rienzo +3

We propose a novel numerical method able to determine efficiently and effectively the relationship of complementarity between portions of proteins surfaces. This innovative and gen…

cond-mat.dis-nn2018★ 34 cited

Effect of dilution in asymmetric recurrent neural networks

Viola Folli, Giorgio Gosti, Marco Leonetti +1

We study with numerical simulation the possible limit behaviors of synchronous discrete-time deterministic recurrent neural networks composed of N binary neurons as a function of a…