Toward a universal model for spatially structured populations
arXiv:2012.06913 · doi:10.1103/PhysRevLett.127.218102
Abstract
A key question in evolution is how likely a mutant is to take over. This depends on natural selection and on stochastic fluctuations. Population spatial structure can impact mutant fixation probabilities. We introduce a model for structured populations on graphs that generalizes previous ones by making migrations independent of birth and death. We demonstrate that by tuning migration asymmetry, the star graph transitions from amplifying to suppressing natural selection. The results from our model are universal in the sense that they do not hinge on a modeling choice of microscopic dynamics or update rules. Instead, they depend on migration asymmetry, which can be experimentally tuned and measured.
arXiv comment30 pages, 12 figures
References in corpus (14)
- Evolutionary dynamics on degree-heterogeneous graphs
- Most undirected random graphs are amplifiers of selection for Birth-death dynamics, but suppressors of selection for death-Birth dynamics
- The duality of spatial death-birth and birth-death processes and limitations of the isothermal theorem
- Counterintuitive properties of the fixation time in network-structured populations
- Limits on amplifiers of natural selection under death-Birth updating
- Fixation and consensus times on a network: a unified approach
- The molecular clock of neutral evolution can be accelerated or slowed by asymmetric spatial structure
- Population genetics on islands connected by an arbitrary network: An analytic approach
- Transient amplifiers of selection and reducers of fixation for death-Birth updating on graphs
- Fitness dependence of the fixation-time distribution for evolutionary dynamics on graphs
- Exact results for fixation probability of bithermal evolutionary graphs
- Fast flowing populations are not well mixed
- Nonmonotonic Effects of Migration in Subdivided Populations
- Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance