Chain reconfiguration in active noise

Abstract

In a typical single molecule experiment, dynamics of an unfolded proteins is studied by determining the reconfiguration time using long-range Forster resonance energy transfer where the reconfiguration time is the characteristic decay time of the position correlation between two residues of the protein. In this paper we theoretically calculate the reconfiguration time for a single flexible polymer in presence of active noise. The study suggests that though the MSD grows faster, the chain reconfiguration is always slower in presence of long-lived active noise with exponential temporal correlation. Similar behavior is observed for a worm like semi-flexible chain and a Zimm chain. However it is primarily the characteristic correlation time of the active noise and not the strength that controls the increase in the reconfiguration time. In a nutshell, such active noise makes the polymer to move faster but the correlation loss between the monomers becomes slower.

18 pages, 8 figures

References in corpus (12)

• Non-equilibrium microtubule fluctuations in a model cytoskeleton
• Effective Temperature of Red Blood Cell Membrane Fluctuations
• How does a flexible chain of active particles swell?
• Unusual swelling of a polymer in a bacterial bath
• Facilitation of polymer looping and giant polymer diffusivity in crowded solutions of active particles
• Kinetics of polymer looping with macromolecular crowding: effects of volume fraction and crowder size
• Dynamics of a polymer in an active and crowded environment
• Depletion effects and loop formation in self-avoiding polymers
• Rouse Modes of Self-avoiding Flexible Polymers
• Looping and reconfiguration dynamics of a flexible chain with internal friction
• Reconfiguration Dynamics in folded and intrinsically disordered protein with internal friction: Effect of solvent quality and denaturant
• Looping dynamics of flexible chain with internal friction at different degree of compactness

Cited by in corpus (36)

• Broken detailed balance and non-equilibrium dynamics in living systems
• The physics of active polymers and filaments
• Globule-like conformation and enhanced diffusion of active polymers
• Conformational properties of active semiflexible polymers
• Dynamics of Active Rouse Chains
• Structure and dynamics of a self-propelled semiflexible filament
• Enhanced diffusion, swelling and slow reconfiguration of a single chain in non-Gaussian active bath
• Nonequilibrium mode-coupling theory for dense active systems of self-propelled particles
• Effects of active fluctuations on energetics of a colloidal particle: superdiffusion, dissipation and entropy production
• Entropy production and work fluctuation relations for a single particle in active bath
• Conformation and dynamics of a self-avoiding active flexible polymer
• Active Brownian filaments with hydrodynamic interactions: conformations and dynamics
• Elasticity-based polymer sorting in active fluids: A Brownian dynamics study
• Escape of a passive particle from activity-induced energy landscape: Emergence of slow and fast effective diffusion
• Translational and rotational dynamics of a self-propelled Janus probe in crowded environments
• Anomalous diffusion for active Brownian particles cross-linked to a networked polymer: Langevin dynamics simulation and theory
• The Coil-Globule transition in self-avoiding active polymers
• Active dynamics and spatially coherent motion in chromosomes subject to enzymatic force dipoles
• Reconfiguration, swelling and tagged monomer dynamics of a single polymer chain in Gaussian and non-Gaussian active baths
• On the generalized Langevin equation for a Rouse bead in a nonequilibrium bath
• Migration of Active Rings in Porous Media
• Hydrodynamics of polymers in an active bath
• Configuration Dynamics of a Flexible Polymer Chain in a Bath of Chiral Active Particles
• Active Dynamics of Linear Chains and Rings in Porous Media
• Non-Gaussian anomalous dynamics in systems of interacting run-and-tumble particles
• Unfolding of a diblock chain and its anomalous diffusion induced by active particles
• A Polymer Chain with Dipolar Active Forces in Connection to Spatial Organization of Chromatin
• Effective forces between active polymers
• Nonequilibrium diffusion of active particles bound to a semi-flexible polymer network: simulations and fractional Langevin equation
• Stochastic resetting and first arrival subjected to Gaussian noise and Poisson white noise
• Characteristic features of self-avoiding active Brownian polymers under linear shear flow
• Conformational statistics of non-equilibrium polymer loops in Rouse model with active loop extrusion
• Spiral folding of a flexible chain of chiral active particles
• Diffusion of an Active Particle Bound to a Generalized Elastic Model: Fractional Langevin Equation
• Entropy production in active Rouse polymers
• Thermodynamic uncertainty relation for systems with active Ornstein-Uhlenbeck particles