Biological implications of dynamical phases in non-equilibrium networks
arXiv:1506.02323 · doi:10.1007/s10955-015-1445-0
Abstract
Biology achieves novel functions like error correction, ultra-sensitivity and accurate concentration measurement at the expense of free energy through Maxwell Demon-like mechanisms. The design principles and free energy trade-offs have been studied for a variety of such mechanisms. In this review, we emphasize a perspective based on dynamical phases that can explain commonalities shared by these mechanisms. Dynamical phases are defined by typical trajectories executed by non-equilibrium systems in the space of internal states. We find that coexistence of dynamical phases can have dramatic consequences for function vs free energy cost trade-offs. Dynamical phases can also provide an intuitive picture of the design principles behind such biological Maxwell Demons.
10 figures. Submitted to the Journal of Statistical Physics (special issue on "Information Processing in Living Systems")
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Cited by in corpus (5)
- Topological localization in out-of-equilibrium dissipative systems
- Topologically protected modes in non-equilibrium stochastic systems
- Trade-offs and thermodynamics of energy-relay proofreading
- Reaction-Path Statistical Mechanics of Enzymatic Kinetics
- Processive and Distributive Non-Equilibrium Networks Discriminate in Alternate Limits