Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranes
arXiv:1407.5504 · doi:10.1038/ncomms6948
Abstract
Short DNA linkers are increasingly being exploited for driving specific self-assembly of Brownian objects. DNA-functionalised colloids can assemble into ordered or amorphous materials with tailored morphology. Recently, the same approach has been applied to compliant units, including emulsion droplets and lipid vesicles. The liquid structure of these substrates introduces new degrees of freedom: the tethers can diffuse and rearrange, radically changing the physics of the interactions. Unlike droplets, vesicles are extremely deformable and DNA-mediated adhesion causes significant shape adjustments. We investigate experimentally the thermal response of pairs and networks of DNA-tethered liposomes and observe two intriguing and possibly useful collective properties: negative thermal expansion and tuneable porosity of the liposome networks. A model providing a thorough understanding of this unexpected phenomenon is developed, explaining the emergent properties out of the interplay between the temperature-dependent deformability of the vesicles and the DNA-mediated adhesive forces.
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Cited by in corpus (14)
- Theory and Simulation of DNA-Coated Colloids: a Guide for Rational Design
- Kinetic control of the coverage of oil droplets by DNA-functionalised colloids
- Programmable interactions with biomimetic DNA linkers at fluid membranes and interfaces
- Colloidal supported lipid bilayers for self-assembly
- Binding equilibrium and kinetics of membrane-anchored receptors and ligands in cell adhesion: insights from computational model systems and theory
- The Role of Optical Projection in the Analysis of Membrane Fluctuations
- Bond formation kinetics affects self-assembly directed by ligand-receptor interactions
- Entropy stabilizes floppy crystals of mobile DNA-coated colloids
- DNA self-organization controls valence in programmable colloid design
- Free energy of ligand-receptor systems forming multimeric complexes
- Steric interactions between mobile ligands facilitate complete wrapping in passive endocytosis
- DNA-coated Functional Oil Droplets
- Surface-triggered cascade reactions between DNA linkers direct self-assembly of colloidal crystals of controllable thickness
- Melting transition in lipid vesicles functionalised by mobile DNA linkers