2.7k citations
- Centre National de la Recherche ScientifiqueFR11 papers
- Université Côte d'AzurFR5 papers
- InsermFR3 papers
- Institut national de recherche en sciences et technologies du numériqueFR3 papers
- Centre Inria d'Université Côte d'AzurFR2 papers
- Laboratoire d'Informatique, Signaux et Systèmes de Sophia AntipolisFR2 papers
- Addenbrooke's HospitalGB1 paper
- Assistance Publique – Hôpitaux de ParisFR1 paper
- ATLANTIS: Modélisation et méthodes numériques pour le calcul d'interactions onde-matière nanostructuréeFR1 paper
- Cambridge University Hospitals NHS Foundation TrustGB1 paper
- CEA Paris-Saclay - Etablissement de Fontenay-aux-rosesFR1 paper
- Center for Infection and Immunity of LilleFR1 paper
4 papers · 1 filter
SENSAAS (SENsitive Surface As A Shape): utilizing open-source algorithms for 3D point cloud alignment of molecules
Dominique Douguet, Frédéric Payan
Open-source 3D data processing libraries originally developed for computer vision and pattern recognition are used to align and compare molecular shapes and sub-shapes. Here, a sha…
A new pharmacological preconditioning-based target: from drosophila to kidney transplantation
Michel Tauc, Nicolas Melis, Miled Bourourou +3
One of the biggest challenges in medicine is to dampen the pathophysiological stress induced by an episode of ischemia. Such stress, due to various pathological or clinical situati…
Requirement for preclinical prioritization of neuroprotective strategies in stroke: Incorporation of preconditioning
Tauskela Joseph S., Blondeau Nicolas
Acute neuroprotection in numerous human clinical trials has been an abject failure. Major systemic-and procedural-based issues have subsequently been identified in both clinical tr…
ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease
Florent Letronne, Geoffroy Laumet, Anne-Marie Ayral +38
Although several ADAMs (A disintegrin-like and metalloproteases) have been shown to contribute to the amy-loid precursor protein (APP) metabolism, the full spectrum of metalloprote…